Ewelina Rojewska Selected Research

Therapeutics

7/2023	Mirogabalin Decreases Pain-like Behaviors by Inhibiting the Microglial/Macrophage Activation, p38MAPK Signaling, and Pronociceptive CCL2 and CCL5 Release in a Mouse Model of Neuropathic Pain.
1/2022	Mirogabalin Decreases Pain-like Behaviours and Improves Opioid and Ketamine Antinociception in a Mouse Model of Neuropathic Pain.
10/2021	The Kynurenine Pathway as a Potential Target for Neuropathic Pain Therapy Design: From Basic Research to Clinical Perspectives.
8/2020	CCR4 antagonist (C021) influences the level of nociceptive factors and enhances the analgesic potency of morphine in a rat model of neuropathic pain.
10/2018	Alterations in the Activity of Spinal and Thalamic Opioid Systems in a Mice Neuropathic Pain Model.
1/2018	Botulinum Toxin Type A-A Modulator of Spinal Neuron-Glia Interactions under Neuropathic Pain Conditions.
11/2016	Participation of pro- and anti-nociceptive interleukins in botulinum toxin A-induced analgesia in a rat model of neuropathic pain.
1/2015	PD98059 Influences Immune Factors and Enhances Opioid Analgesia in Model of Neuropathy.
1/2015	Parthenolide Relieves Pain and Promotes M2 Microglia/Macrophage Polarization in Rat Model of Neuropathy.
7/2014	Expression profiling of genes modulated by minocycline in a rat model of neuropathic pain.

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Ewelina Rojewska Research Topics

Disease

51	Neuralgia (Stump Neuralgia) 07/2023 - 11/2009
28	Pain (Aches) 07/2023 - 09/2013
15	Hypersensitivity (Allergy) 07/2023 - 01/2017
6	Diabetic Neuropathies (Diabetic Neuropathy) 01/2018 - 01/2013
6	Hyperalgesia 02/2016 - 01/2014
3	Chronic Disease (Chronic Diseases) 07/2023 - 01/2018
3	Chronic Pain 10/2021 - 01/2013
1	Peripheral Nervous System Diseases (PNS Diseases) 05/2023
1	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2016
1	Respiratory Insufficiency (Respiratory Failure) 01/2016

Drug/Important Bio-Agent (IBA)

25	Opioid Analgesics (Opioids)IBA 05/2023 - 01/2013
21	Analgesics (Analgesic Drugs)IBA 07/2023 - 01/2013
21	Morphine (MS Contin)FDA LinkGeneric 05/2023 - 09/2013
14	Minocycline (Cyclops)FDA LinkGeneric 01/2018 - 11/2009
13	LigandsIBA 08/2020 - 12/2013
9	Buprenorphine (Subutex)FDA LinkGeneric 01/2022 - 10/2015
7	ChemokinesIBA 07/2020 - 01/2015
6	Neutralizing AntibodiesIBA 01/2022 - 01/2018
5	CytokinesIBA 01/2021 - 11/2009
5	Messenger RNA (mRNA)IBA 01/2019 - 12/2013
5	Streptozocin (Streptozotocin)FDA Link 01/2018 - 01/2013
4	KynurenineIBA 01/2023 - 03/2016
4	Proteins (Proteins, Gene)FDA Link 01/2019 - 12/2014
3	Maraviroc FDA Link 07/2020 - 01/2016
3	Type A Botulinum Toxins (Botox)FDA Link 01/2018 - 11/2016
3	incobotulinumtoxinA FDA Link 01/2018 - 11/2016
3	InterleukinsIBA 01/2017 - 09/2013
3	Antidepressive Agents (Antidepressants)IBA 02/2015 - 01/2013
2	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 07/2023 - 01/2019
2	mirogabalinIBA 07/2023 - 01/2022
2	Phosphotransferases (Kinase)IBA 05/2023 - 09/2013
2	Oxycodone (Oxycontin)FDA LinkGeneric 05/2023 - 01/2022
2	CC ChemokinesIBA 08/2020 - 11/2017
2	Dynorphins (Dynorphin)IBA 04/2020 - 11/2014
2	delta Opioid Receptors (delta Opioid Receptor)IBA 04/2020 - 01/2014
2	zaprinastIBA 02/2019 - 11/2018
2	preproenkephalinIBA 10/2018 - 11/2014
2	Opioid Receptors (Opioid Receptor)IBA 10/2018 - 01/2014
2	Kynurenine 3-Monooxygenase (Kynurenine 3 Monooxygenase)IBA 01/2018 - 03/2016
2	EnzymesIBA 01/2018 - 03/2016
2	NociceptinIBA 01/2016 - 01/2014
2	Amitriptyline (Elavil)FDA LinkGeneric 02/2015 - 01/2013
2	Fluoxetine (Prozac)FDA LinkGeneric 02/2015 - 01/2013
2	Milnacipran (Ixel)FDA Link 02/2015 - 01/2013
2	Doxepin (Mareen)FDA LinkGeneric 02/2015 - 01/2013
2	Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric 02/2015 - 01/2013
2	Pentoxifylline (Trental)FDA LinkGeneric 09/2013 - 11/2009
2	fluorocitrateIBA 09/2013 - 11/2009
2	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2013 - 01/2013
1	Pregabalin (Lyrica)FDA Link 07/2023
1	bardoxolone methylIBA 05/2023
1	artemisinin (artemisinine)IBA 05/2023
1	fisetinIBA 05/2023
1	verticineIBA 05/2023
1	astaxanthine (astaxanthin)IBA 05/2023
1	Ketamine FDA LinkGeneric 01/2022
1	CXC ChemokinesIBA 10/2021
1	Chemokine ReceptorsIBA 10/2021
1	SB328437IBA 01/2021
1	CCR ReceptorsIBA 01/2021
1	HydrazinesIBA 01/2021
1	Dipyrone (Metamizole)IBA 10/2020
1	Non-Narcotic Analgesics (Analgesics, Non Narcotic)IBA 10/2020
1	cenicrivirocIBA 07/2020
1	EnkephalinsIBA 04/2020
1	kappa Opioid Receptors (kappa Opioid Receptor)IBA 04/2020
1	Dopamine (Intropin)FDA LinkGeneric 04/2020
1	Kynurenic Acid (Kynurenate)IBA 02/2019
1	Chemotactic FactorsIBA 01/2019
1	LipopolysaccharidesIBA 12/2018
1	Phosphodiesterase InhibitorsIBA 11/2018
1	Cyclic GMPIBA 11/2018
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 11/2018
1	proenkephalinIBA 10/2018
1	Macrophage Inflammatory Proteins (Macrophage Inflammatory Protein 1)IBA 01/2018
1	UCB 35625IBA 01/2018
1	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 01/2018
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2018
1	AcidsIBA 01/2018
1	kynureninaseIBA 01/2018
1	Tryptophan Oxygenase (Tryptophan 2,3 Dioxygenase)IBA 01/2018
1	(+-)-dichlorobenzoylcyclopropane carboxylic acidIBA 01/2018
1	Blood Glucose (Blood Sugar)IBA 11/2017
1	Botulinum Toxins (Botulinum Toxin)IBA 11/2016
1	Interleukin-18 (Interleukin 18)IBA 03/2016
1	tricarbonyldichlororuthenium (II) dimerIBA 02/2016
1	Carbon MonoxideIBA 02/2016
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2016
1	Peptides (Polypeptides)IBA 01/2016
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2016
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 10/2015
1	parthenolideIBA 01/2015
1	2- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- oneIBA 01/2015

Therapy/Procedure

22	Analgesia 05/2023 - 09/2013
10	Therapeutics 07/2023 - 07/2014
5	Spinal Injections 08/2020 - 11/2017
4	Drug Therapy (Chemotherapy) 07/2023 - 07/2020
2	Intraperitoneal Injections 02/2015 - 11/2009
1	Ligation 11/2018
1	Injections 01/2016